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Amniocentesis has been
done for many years and it is suggested that perhaps
one woman in every 150 many miscarry, over and
above the normal incidence of miscarriage.
A Brief Guide To Prenatal Tests
These days, a pregnant woman receiving
prenatal care will find that having a baby can
involve complex technology and testing. This booklet
presents the most common prenatal test |
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discusses what they test, how accurately they
test, and what risks or side effects there are.
As these questions are answered, it will be easier
for you as a pregnant woman or expectant couple
to decide which tests are appropriate for you.
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Prenatal tests can be divided into two categories:
those which give information about the status of the
mother and baby ( such as urine samples, blood counts,
glucose tolerance test, fetal heart tones, and ultrasound
), and those which information about the genetic makeup
and possible congenital abnormalities of the baby
( such as Alpha-Fetoprotein
[ AFP ], Chorionic Villus Sampling [ CVS ], amniocentesis,
and ultrasound ).
Test For Maternal And Fetal Well-Being
Urine samples can give healthcare providers important
information about how you and your baby are doing.
They are first used to determine pregnancy; then you
will probably be asked to give urine samples at each
prenatal visit. You or your practitioner will insert
a small paper stick into your urine to measure the
amounts of protein, sugar, and sometimes ketones.
Usually, none or only a trace of these will be found.
Too much protein in your urine is one of three symptoms
of pre-eclampsia ( also known as toxemia or pregnancy-induced
hypertension ). All three symptoms ( protein in the
urine, high blood pressure, and usual swelling ) must
be present for toxemia.
Too much sugar may be an indication of gestation
diabetes, a form of diabetes which is found only5
in pregnant women and usually disaqppears soon after
birth.
Ketones in the urine, particulary a problem in early
pregnancy, may indicate actual weight loss for the
mother, which can be unhealthy for the fetus.
All of these test are indicators and further testing
would be necessary to determine if there is a problem
and how serious it is. These are conditions which
can be controlled diet, exercise, and rest.
Urine test are also used to screen for drugs, such
as cocaine, marijuana, and alcohol. Results take two
to three days. Such testing sometimes requires informed
consent, meaning you must understand the purpose of
the test and give your permission to have it administered.
Urine tests are done in the practitioner’s
office and results are given immediately, with no
risk or side effects. Your informed consent is not
required. The results are most accurate when you give
a “ clean sample, “ meaning that you clean
your vulva well with soap and some antiseptic and
give urine from the middle of your flow, although
such accuracy is usually not required each time you
go in. Urinary tract infections, not uncommon for
pregnant women, are detected in urine samples. These
results take one to two days.
Blood tests are taken several times throughout pregnancy.
Your blood contains a wealth of information about
you and the fetus. It can be used to confirm pregnancy
and / or duration if there is reason to think that
the urine test was not accurate. It is most often
used to measure the amount of iron in the blood.
It is normal for pregnant women to have lower iron
( in proportion to their blood volume ) than non-pregnant
women, but it is important to make sure there is
enough iron to support mother and fetus. Results
are given immediately or within a day or so depending
on which type of blood test is done and whether
or not there is equipment to run the test in your
practitioner’s
office. Most blood test do not require informed consent,
and accuracy depends on what you are checking.
Alpha-fetoprotein ( AFP ) is a blood test for indication
of congenital and chromosomal anomalies ( deviations
from normal ) in the baby.
HIV/AIDS testing is also a blood test. The results
take about three weeks, and accuracy depends on when
the test is done in relation to when you may have
been exposed to the virus. If you have shared IV
needles or been otherwise exposed to the AIDS virus
in the last eight to twelve years, then you are at
risk for HIV/AIDS. If exposure was more than six
months before the test, then the results are considered
very accurate. Scientists
and practitioners do not yet understand how HIV is
transmitted from mother to fetus. It is important
to have some kind of counseling before and after
the test to learn the implications of this test for
you and your baby.
Glucose tolerance testing is used to test for gestational
diabetes. Some doctors do this test routinely,
and others do so only when there is some other indication
of a possible problem either from symptoms or a
urine test.
The test involves drinking a very sweet substance
( sometimes on empty stomach ) and testing your blood
an hour later. If this test indicates problems, then
a more accurate test is done in which you drink the
sweet substance and then have blood drawn one, two,
and they are considered to be accurate, particularly
the three-hour test. Risks of drinking such a sweet
substance are unknown. Side effects can include nausea
or headache for a few hours after the test.
Weight gain is another indication of the baby’s
growth and your general health in pregnancy. You will
probably be weighed at each prenatal visit. There
should be consistent, even weight gain throughout
the pregnancy, and you should gain 25 to 45 pounds
altogether. Sudden gain or loss of weight may indicate
problems which need to be investigated further.
Measurement of fundal height is used to assess growth
of the fetus. You will be asked to lie on your back,
and the practitioner will use a tape measure or special
fundal height ruler to measure the distance from the
top of your uterus to your pubic bone. This is done
at each prenatal visit from about 20 weeks on, with
no risks but possible discomfort from having to lie
on your back for those few moments.
Sometimes ultrasound scans are used to determine size
and position of fetus or placenta. They can also be
used to determine certain congenital anomalies. Be
sure you know what the practitioner hopes to learn
from an ultrasound scan before you agree to have one.
Details of the test are discussed under Fetal heart
tones.
Blood pressure is another indication of maternal
and fetal well-being which will be measured at each
visit. It is normal for blood adjusts to the increased
volume of blood in your system, but a sharp rise in
blood pressure could indicate a serious problem. Often
weight gain and blood pressure problems are solved
by changes in diet, exercise, and rest.
Fetal heart tones will be checked at each prenatal
visit after the first 12 or 17 weeks, depending on
what type of equipment is used. The Doppler, a handheld
device which magnifies the sound of the heartbeat,
uses ultrasound technology to pick up the baby’s
heartbeat. Long-term effects of ultrasound exposure
are not known.
It is possible to hear the heartbeat earlier in the
pregnancy with a Doppler than with a fetoscope ( a
stethoscope designed to measure fetal heart tones
), but the value of this is not clear. Fetal heart
rate should be about twice as fast as that of an adult.
A slow or irregular heartbeat many indicate that the
fetus is or has been in some distress.
Amniocentesis is a surgical test in which a needle
is inserted through the abdomen into the womb to withdraw
a sample of amniotic fluid. This fluid contains urine
and skin cells from the baby which can be analyzed
to discover its chromosomal or genetic makeup.
Today it is possible to detect about 200 chromosomal
disorders, most of which are very unusual. This test
may be useful if you know that such a disorder runs
in your family. It is most commonly used to detect
neural tube disorders and Down’s syndrome.
The test is done in the 14th to 18th week of pregnancy
and results take several weeks. Risks include possible
miscarriage ( 1 % ), infection, vaginal bleeding,
leaking from the place where the needle went in, isoimmunization
if mother is Rh+ and fetus is Rh-, and harm to the
baby from the needle. These are rare, but they do
occur.
The test is sometimes performed in the practitioner’s
office, but most often in a hospital or genetic testing
center, It is preceded by an ultrasound to determine
the location of the fetus. A local anesthetic is injected
into the area where the needle will be inserted. Results
are considered to be very accurate, although factors
such as maternal cell contamination, cell culture
failure, and artifacts ( in which the cells in the
lab do not reproduce themselves exactly ) can affect
accuracy of results. The test is sometimes uncomfortable
and can produce considerable anxiety in the two to
four weeks between taking the test and receiving the
result.
Results take one to two weeks. Risks include infection,
bleeding, harm to the fetus, and miscarriage.
Long-term risks of this procedure are unknown.
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